The Merrimack Valley is in the south central part of New Hampshire. I-93, I-89, and Route 3 pass through the region.
From the south and west, take I-91 north through Massachusetts into Vermont. Pick up I-89 near Lebanon, NH, and take it south to Merrimack Valley.
From the south and east, take I-93 north through Massachusetts and into New Hampshire to Merrimack Valley.
From points north: I-93 heads southward through the White Mountain area and into the region. I-93 runs near Salem, Windham, Canobie Lake, Derry, Londonderry, Manchester, Concord, and Canterbury.
I-89 runs past Contoockoo, Hopkinton and Concord.
Route 3 travels through Nashua, Merrimack, Bedford, Manchester, and Concord.
Route 4 takes an east-west route through Northwood, Chichester, and Concord.